Format: Book

In the 1980s, a research team led by Parisian scientists identified several unique DNA sequences, or haplotypes, linked to sickle cell anemia in African populations. After casual observations of how patients managed this painful blood disorder, the researchers in question postulated that the Senegalese type was less severe. The Enculturated Gene traces how this genetic discourse has blotted from view the roles that Senegalese patients and doctors have played in making sickle cell “mild” in a social setting where public health priorities and economic austerity programs have forced people to improvise informal strategies of care.

Duana Fullwiley shows how geneticists, who were fixated on population differences, never investigated the various modalities of self-care that people developed in this context of biomedical scarcity, and how local doctors, confronted with dire cuts in Senegal’s health sector, wittingly accepted the genetic prognosis of better-than-expected health outcomes. Unlike most genetic determinisms that highlight the absoluteness of disease, DNA haplotypes for sickle cell in Senegal did the opposite. As Fullwiley demonstrates, they allowed the condition to remain officially invisible, never to materialize as a health priority. At the same time, scientists’ attribution of a less severe form of Senegalese sickle cell to isolated DNA sequences closed off other explanations of this population’s measured biological success.

The Enculturated Gene reveals how the notion of an advantageous form of sickle cell in this part of West Africa has defined–and obscured–the nature of this illness in Senegal today.

Duana Fullwiley is associate professor of anthropology at Stanford University.

In this book, Italian theoretical philosopher Robert Esposito explores the depths to which the logic and language of immunity has penetrated understandings of self and society. He explores how immunisation as discourse, has become a powerful way to imagine and construct the self and other as oppositional entities, as foreign bodies with the ongoing potential for destructive conflict.

However, by exploring how the logic of immunity functions in law, religion and as a biological mechanism of the body, the author is able to challenge the normative assumption of immunity as that which retains boundaries of external and internal. What is revealed throughout the book is the intrinsic nature of immunity as the doubling back of life itself, to incorporate within the body exactly that external entity which threatens its existence.

Having explored the normative basis of immunity, the book asks if there are other ways to imagine relations of self and other, to reimagine community outside the confines of existing understandings of immunity. This turn is of particular interest for those engaging with interdisciplinary works on antimicrobial resistance that seek to challenge, expand and reformulate existing conceptions of human microbe relations.

If immunity exists and functions not through the maintaining of boundaries, or the balancing of internal and external, but only by virtue of itself being intrinsically internal and external – the continuous exchange of material that by virtue of internal foreignness makes existence possible – we are encouraged to truly reassess how we conceptualise ‘otherness’. Perceiving immunity through this lens allows us to question binary relational categories and to rethink the very basis of relations and community.

This summary was written by PhD Student Maddy Pearson.

With Inclusion, Steven Epstein argues that strategies to achieve diversity in medical research mask deeper problems, ones that might require a different approach and different solutions.

Formal concern with this issue, Epstein shows, is a fairly recent phenomenon. Until the mid-1980s, scientists often studied groups of white, middle-aged men—and assumed that conclusions drawn from studying them would apply to the rest of the population. But struggles involving advocacy groups, experts, and Congress led to reforms that forced researchers to diversify the population from which they drew for clinical research. While the prominence of these inclusive practices has offered hope to traditionally underserved groups, Epstein argues that it has drawn attention away from the tremendous inequalities in health that are rooted not in biology but in society.

This seminal collection of essays critiquing ethnography as literature is augmented with a new foreword by Kim Fortun, exploring the ways in which Writing Culture has changed the face of ethnography over the last 25 years.

James Clifford is Professor, History of Consciousness Department, at the University of California, Santa Cruz. George E. Marcus is Chancellor’s Professor, Department of Anthropology, at the University of California, Irvine.

Development, it is generally assumed, is good and necessary, and in its name the West has intervened, implementing all manner of projects in the impoverished regions of the world. When these projects fail, as they do with astonishing regularity, they nonetheless produce a host of regular and unacknowledged effects, including the expansion of bureaucratic state power and the translation of the political realities of poverty and powerlessness into “technical” problems awaiting solution by “development” agencies and experts. It is the political intelligibility of these effects, along with the process that produces them, that this book seeks to illuminate through a detailed case study of the workings of the “development” industry in one country, Lesotho, and in one “development” project.

Using an anthropological approach grounded in the work of Foucault, James Ferguson analyzes the institutional framework within which such projects are crafted and the nature of “development discourse,” revealing how it is that, despite all the “expertise” that goes into formulating development projects, they nonetheless often demonstrate a startling ignorance of the historical and political realities of the locale they are intended to help. In a close examination of the attempted implementation of the Thaba-Tseka project in Lesotho, Ferguson shows how such a misguided approach plays out, how, in fact, the “development” apparatus in Lesotho acts as an “anti-politics machine,” everywhere whisking political realities out of sight and all the while performing, almost unnoticed, its own pre-eminently political operation of strengthening the state presence in the local region.

A revealing and surprising look at how classification systems can shape both worldviews and social interactions.

What do a seventeenth-century mortality table (whose causes of death include “fainted in a bath,” “frighted,” and “itch”); the identification of South Africans during apartheid as European, Asian, colored, or black; and the separation of machine- from hand-washables have in common? All are examples of classification—the scaffolding of information infrastructures.

In Sorting Things Out, Geoffrey C. Bowker and Susan Leigh Star explore the role of categories and standards in shaping the modern world. In a clear and lively style, they investigate a variety of classification systems, including the International Classification of Diseases, the Nursing Interventions Classification, race classification under apartheid in South Africa, and the classification of viruses and of tuberculosis.

The authors emphasize the role of invisibility in the process by which classification orders human interaction. They examine how categories are made and kept invisible, and how people can change this invisibility when necessary. They also explore systems of classification as part of the built information environment. Much as an urban historian would review highway permits and zoning decisions to tell a city’s story, the authors review archives of classification design to understand how decisions have been made. Sorting Things Out has a moral agenda, for each standard and category valorizes some point of view and silences another. Standards and classifications produce advantage or suffering. Jobs are made and lost; some regions benefit at the expense of others. How these choices are made and how we think about that process are at the moral and political core of this work. The book is an important empirical source for understanding the building of information infrastructures.